… reviews genetic modifier studies in DMD to date and discusses the effect of genetic modifiers
on … (inclusion of genotype-stratified subgroup analyses) and therapeutic approaches. The …

… muscular dystrophy (DMD) phenotype. This meta-analysis aims to estimate the association
of genetic … ) and secreted phosphoprotein 1 (SPP1) genes, among others, with age of loss of …

… genetic modifiers in DMD suggests that the ‘effect size’ of the … Effect size of genetic modifiers
can be quantitated in DMD by … Genetic modifiers to date all show about 1-2 years change in …

… genes different from DMD, that may influence the pathological consequences of dystrophin
… Here we aimed at describing the natural history of, and effect of GC treatment on respiratory …

… of GCs treatment, which is worth further discussing considering GCs has … genetic modifier
of the long-term effect of GCs treatment in Chinese patients with Duchenne muscular dystrophy…

… In this paper, I present the significance of molecular diagnosis and the development of
mutation-based therapeutic strategies to complement or restore dystrophin expression. …

… , structurally complex genes. Targeting compensatory modifier genes could be beneficial
to … a disease-modifying gene associated with congenital muscular dystrophy type 1A (MDC1A) …

… muscles lack dystrophin, efficient gene therapy should allow the expression of a new dystrophin
gene not only in limb muscles but … The estimation of how much dystrophin is required to …

… reported that dystrophin is a tumor suppressor gene and likely … that therapeutic approaches
developed for muscular dystrophies … modifiers, as well as setting up in vitro protocols of gene …

… genetic loci that are associated with a modifier effect on the phenotype of human Duchenne
muscular dystrophy (… These “trans-active” genetic modifiers are the main focus of the present …